Zimmer and ISTO Technologies Announce Phase III Clinical Study to Evaluate the Effectiveness of Engineered Juvenile Cartilage to Repair Damaged Knees

Zimmer Holdings, Inc. (NYSE and SIX: ZMH), a global leader in musculoskeletal health, and ISTO Technologies, Inc., an orthobiologics company focused on developing breakthrough products to regenerate and restore function to damaged cartilage and bone, today announced a Phase III clinical study to evaluate DeNovo® ET Engineered Tissue Graft, an engineered cartilage implant intended to repair cartilage defects in the knee. DeNovo ET Graft is being developed under a collaborative relationship between ISTO and Zimmer.

"The DeNovo ET Graft program represents a natural extension to our early intervention and joint preservation portfolio," said Cheryl R. Blanchard, Ph.D., Senior Vice President and Chief Scientific Officer at Zimmer. "This Phase III study will generate meaningful data on the potential of this novel biological solution for treatment of cartilage lesions earlier in the continuum of care."

Zimmer объявил о приобретении Synvasive Technology, Inc.

Zimmer объявил о приобретении Synvasive Technology, Inc.

Zimmer Holdings, Inc. (NYSE and SIX: ZMH) announced today that it has acquired Reno, Nevada-based Synvasive Technology, Inc. The acquisition will enhance Zimmer's product portfolio through the addition of Synvasive's STABLECUT® surgical saw blades, as well as the eLIBRA® Dynamic Knee Balancing System™ for soft tissue balancing.


"Zimmer is committed to developing the industry's most innovative range of technologies to support personalized therapies, from improved surgical power equipment to patient specific instrumentation and other intelligent tools that support optimal surgical outcomes," said Jeff McCaulley, President, Zimmer Reconstructive. "The acquisition of Synvasive Technology further strengthens our surgical resection and advanced instrumentation offerings."


In the surgical resection market, Synvasive has long been recognized as a leader in surgical cutting tools with its STABLECUT® blades. Synvasive's eLIBRA® Dynamic Knee Balancing System™ is the premiere soft-tissue balancing solution in the industry. This offering provides patient specific soft-tissue balancing during knee replacement surgery, establishing the optimal position of the femoral implant to enable a less-invasive surgical approach as well as excellent stability, range of motion and patella tracking.